DISCLAIMER
These products and services, as all other natural supplements, are not evaluated by the Food and Drug Administration.
Therefore, these statements contained herein are for informational purposes only.
These products and services are not intended to diagnose, treat, cure or prevent disease.
Always consult with your professional Health Care provider before beginning dietary supplementation.
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Other Genova Diagnostics Laboratory Home Test Kits
The Genova Diagnostics Lab
...formerly called The Great Smokies Diagnostic Laboratory...
located in Asheville, NC
is the only lab used by the
International Institute of Holistic Healing for testing.
It is among the most modern and sophisticated labs,
fully equipped with "state-of-the-art" tools for precise and sensitive analysis.
This lab is recognized to be a scientific world leader
using the highest standards in the industry,
and is managed by extremely knowledgeable chemists and microbiologists.
It is trusted by thousands of Healthcare Practitioners globally
to yield the most reliable results in their assessment of body specimens for physiological function.
All samples are analyzed under rigorously controlled conditions, providing information available almost nowhere else.
The tests frequently pinpoint the cause of chronic ailments and ailments that typically evade conventional analysis.
Specimens and results are sent by Airborne Express expedited delivery.
All clients are sent a copy of their results in
easy-to-understand language.
Note: The lab does not test for drugs.
ANMA Naturopathic Nutritional Consultant
Washington, DC Registered Naturopath
Board-Certified by the American Naturopathic Medical Association
International Institute of Holistic Healing, Inc.
Mailing Address: PO Box 944, Lancaster, TX 75146 USA
Physical Location: 2331 Gus Thomasson, Suite 115, Dallas, TX 75228, USA
Business Tel. 972 227-3445 Fax Tel. 972 227-2251
E-mail: Adams@DoctorAJAdams.com Website: www.DoctorAJAdams.com
Click HERE for Nutrition Course to Become a Certified Nutritional Consultant
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Become a Certified Nutritional Consultant
Genova Labs Home Test Kits--Stool, Urine, Hair
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About Aundrea Adams
Intestinal Permeability Assessment...Urine Test for Leaky Gut...$111
In-Home Lab Test Kit
This test is a powerful and non-invasive assessment of small intestinal absorption and barrier function in the bowel. This test analyzes urine for the clearance of two non-metabolized sugars, lactulose and mannitol. The Intestinal Permeability Assessment directly measures the ability of two nonmetabolized sugar molecules mannitol and lactuloseto permeate the intestinal mucosa. Mannitol is easily absorbed and serves as a marker of transcellular uptake, while lactulose is only slightly absorbed and serves as a marker for mucosal integrity. To perform the test, the patient mixes premeasured amounts of lactulose and mannitol and drinks the challenge substance. The test measures the amount of lactulose and mannitol recovered in a urine sample over the next 6 hours.
This test identifies Leaky Gut and malabsorption. Leaky Gut is the name of the syndrome describing an unfavorable increase in intestinal permeability which causes nutrients to leak out. Undigested macromolecule food particles and toxins are allowed to pass directly into the body, creating a variety of problems including triggering an immune response sensitizing the individual to normally harmless molecules. When this occurs some people become hypersensitive to environmental substances or develop multiple food allergies. These undigested particles may also pass through the blood-brain barrier where they can be mistaken for neurotransmitters, leading to mental symptoms that may create abnormal behavior. The small intestine has the paradoxical dual function of being a digestive/ absorptive organ for nutrients as well as a powerful barrier against the excessive absorption of bacteria, food antigens and large molecules. Increased permeability of the intestinal mucosal barrier can swell the number of toxins and antigens entering the bloodstream and lead to an overly sensitized immune system in some individuals. Decreased permeability, on the other hand, appears as a fundamental cause of malnutrition, malabsorption and failure to thrive. A number of clinical disorders are associated with both conditions.
In other words, the small intestine has to be able to both digest and absorb nutrients. It also has the important immune function of keeping out excessive absorption of bacteria, substances that trigger allergies, and other large toxic compounds that do not belong in the body. If the gut is too permeable [leaky gut], these substances will penetrate the intestinal barrier, invade the bloodstream and lymph system, overwhelm the liver's detoxification system, and cause an overly sensitive immune system. Intestinal permeability may be affected by several factors, including intestinal infection, ingestion of allergy-causing foods, toxic chemicals, trauma, blood poisoning, alcoholism, and NSAIDS [non-steroidal anti-inflammatory medications], such as Ibuprofen and Naproxen.
Both malabsorption and increased intestinal permeability ["leaky gut"] are associated with chronic gastrointestinal imbalances as well as many systemic disorders, such as...
- IBS [Inflammatory Bowel Disease]
- Gastritis, Colitis, Ileitis, Crohn's Disease
- Food Allergies
- Inflammatory Joint Disease [Arthritis]
- Chronic Skin Disorders
- Malabsorption
- Failure To Thrive
- Worsening Of Gluten Sensitivity
Increased permeability of the small intestine can:
- Increase the number of foreign compounds entering the bloodstream.
- Allow bacterial antigens capable of cross-reacting with host tissue to enter the bloodstream, leading to auto-immune processes.
- Enhance the uptake of toxic compounds that can overwhelm the hepatic detoxification system and lead to an overly sensitized immune system.
Increased gut permeability has been observed in a range of disorders such as:
- Inflammatory Bowel Disease (IBD)
- Food allergy
- Inflammatory joint disease
- Chronic dermatologic conditions
Studies have demonstrated that the increased permeability observed in patients with ankylosing spondylitis, rheumatoid arthritis, and vasculitis may be an important factor in the pathogenesis of these disorders.
Decreased permeability, on the other hand, appears as a fundamental cause of malabsorption, subsequent malnutrition, and failure to thrive. In certain disease states of the small intestine, such as gluten-sensitive enteropathy, permeability to largemoleculesmay increasewhile permeability to smallmolecules decreases, a result of damage to themicrovilli. As a result, nutrients become even less available to assist in the detoxification of antigens flooding the system.
Possible causes of intestinal permeability include:
- Intestinal infection
- Ingestion of allergenic foods or toxic chemicals
- Deficient secretory IgA
- Trauma and endotoxemia
- NSAIDs
Frequently Asked Questions
What does this test involve?
Following an overnight fast (at least 8 hours), you will drink a "challenge" drink of 2 sugars (lactulose and mannitol). You will then collect your urine for the next 6 hours.
Do I have to fast for the entire 6 hours?
No, you will fast for only the first 2 hours after taking the test drink. You may eat and drink normally after this point.
Do I have to avoid certain foods?
Yes, it is important to stop eating or drinking any substances containing fructose (fruit sugar) during the 6 hour collection, as this will interfere with test results. This includes all fruits, fruit juices, soft drinks sweetened with high-fructose corn syrup, dietetic foods such as jams and jellies, chocolate and honey. Check labels carefully.
Can I drink water?
Yes, it is important that you drink a glass of water 2 hours after taking the test drink, and then at least 1 cup of water every hour until you finish your collection. I.e. there is no limit after the 2 hour point.
Will the lactulose/mannitol solution make me gain weight?
No, neither sugar is metabolized by your body.
Can the drink make me feel sick?
In some individuals, it may cause a stomach ache or diarrhea.
I am diabetic. Will that affect the test results?
Abnormally high glucose can interfere with the test. Please discuss this with your clinician.
What medications can affect my test results?
Aspirin and non-steroidal anti-inflammatory drugs (e.g. ibuprofen) may affect the results, although your health care practitioner may choose to examine their influence on gut permeability. Please discuss any medications you are using with him or her.
Can this test be done on a child that is not potty trained?
No, because the urine can be lost in diapers, e.g.
Does a child drink the entire bottle of lactulose/mannitol?
Yes, the child takes the same dose as an adult.
Should I refrigerate the urine samples?
Yes, it is important to refrigerate them if you cannot ship your kit to the lab on the day you complete the test.
What nutritional supplements should I take to help repair a leaky gut?
Please read the following instructions before ordering:
•You may click HERE to place an ON-LINE order below using a CREDIT CARD, CASH or E-CHECK. In the submission box below, you must enter the first and last name of the person taking the test.
You may click HERE to place an ON-LINE order below using a CREDIT CARD, CASH or E-CHECK. In the submission box below, you must enter the first and last name of the person taking the test. •You may also place a telephone order at 817 457-1232. Telephone order hours are 8 AM - 4 PM CST Monday-Friday.
You may also place a telephone order at 817 457-1232. Telephone order hours are 8 AM - 4 PM CST Monday-Friday. •You may also place an order by Fax. The Fax number is 972 227-2251 and is open 24 hours per day.
You may also place an order by Fax. The Fax number is 972 227-2251 and is open 24 hours per day. •The postal address to place orders using a Check or Money Order is:
The postal address to place orders using a Check or Money Order is: A J Adams, ND
International Institute of Holistic Healing
PO Box 944
Lancaster, TX 75146 USA
•Upon purchase, your test kit(s) will be shipped to you directly from Genova Diagnostics Labs via FedEx Ground. Please allow approximately 3 - 5 days for delivery.
Upon purchase, your test kit(s) will be shipped to you directly from Genova Diagnostics Labs via FedEx Ground. Please allow approximately 3 - 5 days for delivery. •When you receive the test kit, you will follow instructions to collect the sample. You will then mail the sample to Genova Labs in their postage-paid package. After Genova Diagnostics Labs complete the test, they will send the results to my office. Your results will then be mailed to you via USPS First Class mail. After the lab receives your specimen, the results usually arrive to you within 10-14 BUSINESS DAYS. If you have not received your results after 21 BUSINESS DAYS, please email Adams@DoctorAJAdams.com
When you receive the test kit, you will follow instructions to collect the sample. You will then mail the sample to Genova Labs in their postage-paid package. After Genova Diagnostics Labs complete the test, they will send the results to my office. Your results will then be mailed to you via USPS First Class mail. After the lab receives your specimen, the results usually arrive to you within 10-14 BUSINESS DAYS. If you have not received your results after 21 BUSINESS DAYS, please email Adams@DoctorAJAdams.com•The Genova Labs reports are generally easy to understand. They include a comprehensive detailed report, and SOME of them include their suggested treatment plan which may include a medical protocol. As an alternative, upon your request, I will be happy to provide you with a FREE Naturopathic comprehensive consult for your signs/symptoms.
The Genova Labs reports are generally easy to understand. They include a comprehensive detailed report, and SOME of them include their suggested treatment plan which may include a medical protocol. As an alternative, upon your request, I will be happy to provide you with a FREE Naturopathic comprehensive consult for your signs/symptoms.